sAJM589 |
| Catalog No.GC38845 |
sAJM589는 1.8μM의 IC50으로 Myc-Max 이종이량체를 강력하게 파괴하는 Myc 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2089-82-9
Sample solution is provided at 25 µL, 10mM.
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sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM[1].
sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC50 of 1.8 μM[1].sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].
[1]. Choi SH, et al. Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. ACS Chem Biol. 2017 Nov 17;12(11):2715-2719.
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