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Sintilimab

Catalog No.GC65290

신틸리맙(IBI308)은 PD-1에 결합하여 PD-1과 리간드(PD-L1 및 PL-L2)의 상호작용을 차단하고 결과적으로 내인성 항종양 T 세포 반응을 회복시키는 데 도움이 되는 완전한 인간 IgG4 단일클론 항체입니다. .

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Sintilimab Chemical Structure

Cas No.: 2072873-06-2

Size 가격 재고 수량
1mg
US$187.00
재고 있음
5mg
US$468.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Sintilimab (IBI308) is a fully human IgG4 monoclonal antibody that binds to PD-1, thereby blocking the interaction of PD-1 with its ligands (PD-L1 and PL-L2) and consequently helping to restore the endogenous antitumour T-cell response. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer[1].

[1]. Sheridan M Hoy. Sintilimab: First Global Approval Drugs. 2019 Feb;79(3):341-346.

리뷰

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