TAT-GluA2 3Y |
Catalog No.GC50582 |
간섭 펩티드인 TAT-GluA2 3Y는 AMPAR의 세포내이입을 방해하여 글루타메이트성 시냅스에서 장기 우울증(LTD)을 차단합니다.
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Cas No.: 1404188-93-7
Sample solution is provided at 25 µL, 10mM.
Inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in rats. Also exhibits antinociceptive effects in a rat model of neuropathic pain. Rescues pentobarbital-induced memory retrieval deficits in a rat model of learning and memory.
Wang et al (2018) Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression. Behav.Brain Res. 339 66 PMID:29162383
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