>>Signaling Pathways>> Membrane Transporter/Ion Channel>> AMPAR>>TAT-GluA2 3Y

TAT-GluA2 3Y

Catalog No.GC50582

간섭 펩티드인 TAT-GluA2 3Y는 AMPAR의 세포내이입을 방해하여 글루타메이트성 시냅스에서 장기 우울증(LTD)을 차단합니다.

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TAT-GluA2 3Y Chemical Structure

Cas No.: 1404188-93-7

Size 가격 재고 수량
1 mg
US$162.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Inhibitor of AMPA receptor endocytosis. Induces increased hind paw withdrawal latencies following thermal and mechanical stimuli in rats. Also exhibits antinociceptive effects in a rat model of neuropathic pain. Rescues pentobarbital-induced memory retrieval deficits in a rat model of learning and memory.

Wang et al (2018) Inhibition of AMPAR endocytosis alleviates pentobarbital-induced spatial memory deficits and synaptic depression. Behav.Brain Res. 339 66 PMID:29162383

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