Thalidomide 4'-oxyacetamide-PEG4-amine |
| Catalog No.GC50463 |
탈리도마이드 4'-옥시아세트아미드-PEG4-아민, 탈리도마이드 기반 세레블론 리간드 및 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체는 PROTAC의 합성에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-85-0
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 2 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Drug development. Phthalimide conjugation as a strategy for in vivo target protein degradation. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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