Thalidomide-NH-PEG2-C2-NH-Boc |
| Catalog No.GC39675 |
탈리도마이드-NH-PEG2-C2-NH-Boc는 탈리도마이드 기반 세레블론 리간드와 dBRD9(화합물 6) 합성에 사용되는 PEG 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다. dBRD9는 BAF 복합 생물학 연구를 위한 선택적 BRD9 프로브 PROTAC 분해제입니다.
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Cas No.: 2097509-40-3
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].
[1]. David Remillard, et al. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.2017 May 15;56(21):5738-5743.
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