Thalidomide-O-PEG2-propargyl (Synonyms: E3 ligase Ligand-Linker Conjugates 32) |
Catalog No.GC38861 |
탈리도마이드-O-PEG2-프로파길(E3 리가제 리간드-링커 접합체 32)은 PROTAC 기술에 사용되는 탈리도마이드 기반 세레블론 리간드 및 2-단위 PEG 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다.
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Cas No.: 2098487-52-4
Sample solution is provided at 25 µL, 10mM.
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
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