TNP (Synonyms: IP3K Inhibitor, IP6K Inhibitor) |
| Catalog No.GC17758 |
TNP는 IP6K1 및 IP3K의 세포 투과성 억제제이며 IC50 값은 IP3K에 대해 각각 0.55μM 및 10.2μM입니다. TNP는 두 효소의 ATP 결합 부위에 결합합니다.
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Cas No.: 519178-28-0
Sample solution is provided at 25 µL, 10mM.
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TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].
References:
[1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.
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