USP5-IN-1 |
| Catalog No.GC66438 |
USP5-IN-1 (화합물 64)은 강력한 디유비퀴티네이스 USP5 억제제로, USP5 ZnF-UBD에 KD 값이 2.8 μM으로 결합합니다. USP5-IN-1은 구조적으로 유사한 ZnF-UBD 도메인을 포함하는 아황산염 단백질 9종보다 선택적입니다. USP5-IN-1은 di-ubiquitin 기질의 USP5 촉매 절단을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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USP5-IN-1 (compound 64), a potent deubiquitinase USP5 inhibitor, binds to the USP5 ZnF-UBD with a KD of 2.8 μM. USP5-IN-1 is selective over nine proteins containing structurally similar ZnF-UBD domains. USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate[1].
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