>>Signaling Pathways>> Cell Cycle/Checkpoint>> Proteolysis>>Z-IETD-AFC

Z-IETD-AFC (Synonyms: Z-Ile-Glu-Thr-Asp-7-amino-4-Trifluormethylcoumarin)

Catalog No.GC45181

특정 형광 기질인 Z-IETD-AFC를 사용하여 카스파제-8 촉매 활성을 결정할 수 있습니다.

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Z-IETD-AFC Chemical Structure

Cas No.: 219138-02-0

Size 가격 재고 수량
1mg
US$46.00
재고 있음
5mg
US$222.00
재고 있음
10mg
US$389.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B. Upon enzymatic cleavage by caspase-8 or granzyme B, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-8 or granzyme B activity. AFC displays excitation/emission maxima of 380/500 nm, respectively.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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