Zilovertamab (Synonyms: UC-961; Cirmtuzumab) |
| Catalog No.GC66327 |
Zilovertamab(UC-961)은 Wnt5a 유도 ROR1 신호 전달을 차단하는 ROR1에 대한 인간화 단일 클론 항체입니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling[1].
Zilovertamab (25 and 50 µg/mL; 72 h) inhibits high-grade serous ovarian cancer (HGSOC) cell proliferation[1].
Zilovertamab (50 µg/mL; 72 h) down-regulates ROR1 expression levels in CaOV3 at the transcriptional level[1].
Cell Proliferation Assay[1]
| Cell Line: | CaOV3, CaOV3CisR, PEO1, and PEO4 cells |
| Concentration: | 25 and 50 µg/mL |
| Incubation Time: | 72 hours |
| Result: | Reduced the proliferation of CaOV3, CaOV3CisR and PEO1. |
Western Blot Analysis[1]
| Cell Line: | CaOV3, CaOV3CisR, PEO1, and PEO4 cells |
| Concentration: | 50 µg/mL |
| Incubation Time: | 72 hours |
| Result: | Down-regulated ROR1 expression levels in CaOV3 at the transcriptional level. |
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *