DNA Damage/DNA Repair
Research Areas
- MTH1(4)
- PARP(103)
- ATM/ATR(31)
- DNA Alkylating(23)
- DNA Ligases(3)
- DNA Methyltransferase(27)
- DNA-PK(28)
- HDAC(143)
- Nucleoside Antimetabolite/Analogue(194)
- Telomerase(15)
- Topoisomerase(193)
- tankyrase(5)
- Antifolate(33)
- CDK(299)
- Checkpoint Kinase (Chk)(36)
- CRISPR/Cas9(9)
- Deubiquitinase(84)
- DNA Alkylator/Crosslinker(87)
- DNA/RNA Synthesis(575)
- Eukaryotic Initiation Factor (eIF)(33)
- IRE1(25)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(59)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(5)
- Early 2 Factor (E2F)(2)
- Zinc Finger Protein(1)
Products Related to DNA Damage/DNA Repair(1968)
- GC81892Vevorisertib tetrahydrochloridePurity: >98.00%
Vevorisertib tetrahydrochloride (ARQ 751 tetrahydrochloride) is an orally active allosteric AKT inhibitor that blocks AKT phosphorylation.
- GC90794Adenosine 5'-methylenediphosphate (sodium salt)CAS: 2659222-76-9Purity: >98.00%
An inhibitor of ecto-5’-nucleotidase
- GC907965-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (sodium salt)CAS: 85280-65-5Purity: >98.00%
An amine-modified nucleotide
- GC908032',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)CAS: 99827-72-2Purity: >95.00%
A reverse transcriptase inhibitor and an active metabolite of ddA and ddI
- GC908235-(3-Aminoallyl)uridine-5'-O-triphosphate (sodium salt)CAS: 85280-66-6Purity: >95.00%
An amine-modified nucleotide
- GC908418-Chloroadenosine-5'-triphosphate (sodium salt)CAS: 793671-47-3Purity: >95.00%
An active metabolite of 8-chloro cAMP
- GC908998-Aminoadenosine-5'-O-triphosphate (sodium salt)CAS: 35892-97-8Purity: >95.00%
An aminated derivative of ATP
- GC90925Thymidine-5'-O-(α,β-methylene)diphosphate (sodium salt)CAS: 71370-60-0Purity: >95.00%
A derivative of TDP and an inhibitor of thymidine kinase
- GC909608-Bromo-2'-deoxyadenosine-5'-O-triphosphate (sodium salt)CAS: 1188369-62-1Purity: >95.00%
A dATP derivative
- GC909763'-O-Methylguanosine-5'-O-triphosphate (sodium salt)CAS: 98923-57-0Purity: >95.00%
A methylated derivative of GTP
- GC91790AMG PERK 44 (hydrochloride)Purity: >98.00%
AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM).
- GC91899Carmustine-d8Purity: >99.00%
Carmustine-d8 is intended for use as an internal standard for the quantification of carmustine by GC- or LC-MS.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81892 | Vevorisertib tetrahydrochloride | - | >98.00% | |
Vevorisertib tetrahydrochloride (ARQ 751 tetrahydrochloride) is an orally active allosteric AKT inhibitor that blocks AKT phosphorylation. | ||||
| GC90483 | Magainin 1 (trifluoroacetate salt) | - | >95.00% | |
An antimicrobial cationic peptide | ||||
| GC90549 | 5-Aminoimidazole-4-carboxamide (hydrate) | - | >95.00% | |
A synthetic precursor | ||||
| GC90657 | COMC | 106281-45-2 | >90.00% | |
An anticancer agent | ||||
| GC90669 | Negamycin (hydrochloride) | - | >80.00% | |
An antibiotic | ||||
| GC90683 | ZM 522 | 1454575-38-2 | >98.00% | |
An inhibitor of ecto-5’-nucleotidase | ||||
| GC90794 | Adenosine 5'-methylenediphosphate (sodium salt) | 2659222-76-9 | >98.00% | |
An inhibitor of ecto-5’-nucleotidase | ||||
| GC90796 | 5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (sodium salt) | 85280-65-5 | >98.00% | |
An amine-modified nucleotide | ||||
| GC90803 | 2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt) | 99827-72-2 | >95.00% | |
A reverse transcriptase inhibitor and an active metabolite of ddA and ddI | ||||
| GC90823 | 5-(3-Aminoallyl)uridine-5'-O-triphosphate (sodium salt) | 85280-66-6 | >95.00% | |
An amine-modified nucleotide | ||||
| GC90841 | 8-Chloroadenosine-5'-triphosphate (sodium salt) | 793671-47-3 | >95.00% | |
An active metabolite of 8-chloro cAMP | ||||
| GC90899 | 8-Aminoadenosine-5'-O-triphosphate (sodium salt) | 35892-97-8 | >95.00% | |
An aminated derivative of ATP | ||||
| GC90925 | Thymidine-5'-O-(α,β-methylene)diphosphate (sodium salt) | 71370-60-0 | >95.00% | |
A derivative of TDP and an inhibitor of thymidine kinase | ||||
| GC90960 | 8-Bromo-2'-deoxyadenosine-5'-O-triphosphate (sodium salt) | 1188369-62-1 | >95.00% | |
A dATP derivative | ||||
| GC90976 | 3'-O-Methylguanosine-5'-O-triphosphate (sodium salt) | 98923-57-0 | >95.00% | |
A methylated derivative of GTP | ||||
| GC91113 | A011 | - | >95.00% | |
An inhibitor of ATM kinase | ||||
| GC91142 | Griselimycin | 26034-16-2 | >98.00% | |
A cyclic depsipeptide with antibacterial activity | ||||
| GC91176 | AOH1996 | 2089314-64-5 | >99.00% | |
An inhibitor of PCNA | ||||
| GC91297 | Cholesterol-Doxorubicin | - | >95.00% | |
A prodrug form of doxorubicin | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 is an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, (IC50s = 5.35, 4.6, 28, 28, and 78 nM, respectively). | ||||
| GC91435 | YCH1899 | - | >98.00% | |
YCH1899 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 1 It is selective for PARP1 and PARP2 over PARP3, -4, -5A, -5B, -6, -7, -10, and -12 (IC50s = 1-14.1 nM). | ||||
| GC91790 | AMG PERK 44 (hydrochloride) | - | >98.00% | |
AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM). | ||||
| GC91899 | Carmustine-d8 | - | >99.00% | |
Carmustine-d8 is intended for use as an internal standard for the quantification of carmustine by GC- or LC-MS. | ||||
| GD01599 | Azocasein | 102110-74-7 | - | |
Azocasein is a useful tracer molecule for characterizing the permeability of the top coat of the multilayer-coated polyester threads. | ||||