Home >> Signaling Pathways >> DNA Damage/DNA Repair >> DNA-PK


DNA-PK is a serine/threonine kinase and acts a molecular sensor for DNA damage. It is involved in NHEJ (non-homologous end joining) for DSB (DNA double strand break) repair and V(D)J recombination.

  1. Cat.No. Product Name Information
  2. GC34444 (R)-Nedisertib
  3. GC16654 CC-115 mTOR/DNA-PK inhibitor
  4. GC34121 CC-115 hydrochloride
  5. GC10812 Compound 401 DNA-PK and mTOR inhibitor
  6. GC11175 Daun02 Cell viability inhibitor,DNA synthisis inhibitor
  7. GC16582 DMNB DNA-dependent protein kinase (DNA-PK) inhibitor
  8. GC10196 ETP-46464 ATR inhibitor,potent and selective
  9. GC14346 KU-0060648 Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  10. GC19227 LTURM34 LTURM34 is a specific DNA-PK inhibitor with an IC50 of 0.034 uM.
  11. GC15485 LY 294002

    Potent PI3K inhibitor

  12. GC14371 LY3023414 class I PI3K isoforms, mTOR and DNA-PK inhibitor
  13. GC32718 M3814 (nedisertib)
  14. GC12332 NU 7026 DNPK inhibitor,ATP-competitive and potent
  15. GC11251 NU7441 (KU-57788) DNA-PK inhibitor
  16. GC11165 PI-103 Class I PI3K, mTOR and DNA-PK inhibitor
  17. GC16379 PI-103 Hydrochloride DNA-PK/PI 3-kinase/mTOR inhibitor
  18. GC16904 PIK-75 Inhibitor of PI3K isoform p110α
  19. GC17199 PIK-90 PI3K inhibitor,potent selective
  20. GC34749 Rac-Nedisertib
  21. GC19328 SF2523 SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.

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