- Cat.No. Nombre del producto Información
- GC44947 SRS16-86 SRS16-86 es un potente inhibidor de la ferroptosis.
- GC43373 D-Amino Acid Oxidase Inhibitor D-Amino acid oxidase inhibitor is an inhibitor of D-amino acid oxidase (DAAO) with IC50 values of 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively.
- GP10126 Diazepam-Binding Inhibitor Fragment, human Diazepam-Binding Inhibitor (DBI) Fragment is encoded by the DBI gene in human.
- GC47931 PDE4B Inhibitor A PDE4B inhibitor
- GC40105 βARK1 Inhibitor βInhibidor de ARK1 (5-[2-(5-nitro-2-furil)vinil]-2-furoato de metilo) es un inhibidor de GRK2 (β-ARK1).
- GC30892 Glutaminyl Cyclase Inhibitor 1 El inhibidor de glutaminil ciclasa 1 es un inhibidor de glutaminil ciclasa con una IC50 de 0,5 μM.
- GC18875 GSK3β Inhibitor XVIII An inhibitor of GSK3β
- GC18464 β-Secretase Inhibitor IV El inhibidor de β-secretasa IV es un potente inhibidor de BACE-1 activo en células con IC50 de 15,6 y 16,3 nM en concentraciones de BACE-1 de 2 nM y 100 pM, respectivamente.
- GC31558 CCK-A receptor inhibitor 1 El inhibidor 1 del receptor CCK-A es un inhibidor del receptor de colecistoquinina A (CCK-A) con un IC50 de 340 nM.
- GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt) A Bax inhibitor
- GC36156 Glutaminyl Cyclase Inhibitor 3 El inhibidor de glutaminil ciclasa 3 (compuesto 212), un compuesto anti-Alzheimer diseÑado, es un potente inhibidor de la glutaminil ciclasa humana (GC), con una IC50 de 4,5 nM.
- GC44978 Syk Inhibitor II Syk Inhibitor II es un inhibidor de Syk potente, altamente selectivo y competitivo con ATP con una IC50 de 41 nM.
- GC35432 Autocamtide-2-related inhibitory peptide (TFA)
- GC44431 nNOS Inhibitor I El inhibidor I de la nNOS es un inhibidor de la nNOS selectivo y permeable a las células con una Ki de 120 nM.
- GC31110 Glutaminyl Cyclase Inhibitor 2 El inhibidor de glutaminil ciclasa 2 es un inhibidor de la glutaminil ciclasa con una IC50 de 1,23 μM.
- GC44237 MMP-9 Inhibitor I MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).
- GC18315 Calpain Inhibitor VI Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM).
- GC17329 MLCK inhibitor peptide 18 El péptido 18 inhibidor de MLCK es un inhibidor de la quinasa de cadena ligera de miosina (MLCK) con una IC50 de 50 nM e inhibe la CaM quinasa II solo a concentraciones 4000 veces mayores.
- GC50305 Autocamtide-2-related inhibitory peptide, myristoylated El péptido inhibidor relacionado con Autocamtide-2, miristoilado es el péptido inhibidor relacionado con Autocamtide-2 miristoilado.
- GC52154 Inflammasome Inhibitor 4b
- GC47962 PKCε Inhibitor Scramble Peptide A negative control for PKCε inhibitor peptide
- GC48030 RC574 An inhibitor of ferroptosis
- GC48029 RC363 An inhibitor of ferroptosis
- GC43329 Cu-ATSM Cu-ATSM es un antioxidante que atrapa radicales (RTA) altamente potente e inhibidor de la peroxidación de (fosfolípidos), lo que explica su (su) capacidad para inhibir la ferroptosis.
- GC40922 SRS11-92 SRS11-92, un anÁlogo de Ferrostatin-1 (Fer-1), es un potente inhibidor de la ferroptosis.
- GC26035 Verubecestat (MK-8931) Trifluoroacetate Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
-
GC33715
Fluoxetine (LY-110140)
Un inhibidor selectivo de la recaptación de serotonina para investigación antidepresiva.
- GC11517 SEA0400 A selective inhibitor of the Na+/Ca2+ exchanger
- GC10267 Rivastigmine A cholinesterase inhibitor
- GC11743 MF63 A potent, selective, and orally active mPGES-1 inhibitor
-
GC10629
KN-93
Inhibidor selectivo de la quinasa tipo II dependiente de Ca2+/calmodulina.
- GC15988 KN-92 hydrochloride An inactive control compound for a CaMKII inhibitor
- GC14132 KN-92 An inactive control compound for a CaMKII inhibitor
- GC17419 Iguratimod A DMARD and COX-2 inhibitor
- GC16573 Galanthamine An alkaloid with AChE inhibitory and nAChR potentiating activities
- GC11768 FK 3311 A COX-2 inhibitor
- GC10429 Etoricoxib A selective COX-2 inhibitor
- GC17921 Tolcapone A reversible COMT inhibitor
- GC12801 Rasagiline Mesylate An inhibitor of MAO-B
- GC17791 LY2811376 A BACE1 inhibitor
- GC15706 Aspirin (Acetylsalicylic acid) A non-selective, irreversible COX inhibitor
- GC12096 Semagacestat (LY450139) A pan γ-secretase inhibitor
- GC14202 KN-62 Inhibitor of Ca2+/calmodulin-dependent kinase type II
-
GC11058
Scrambled 10Panx
Panx-1 mimetic inhibitory peptide, blocks pannexin-1 gap junctions
- GC13863 10Panx A peptide inhibitor of PANX1
- GC11965 (±)-Huperzine A A neuroprotective AChE inhibitor
- GC25708 Paroxetine mesylate Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.
- GC25387 Ethyl (triphenylphosphoranylidene) acetate Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
- GC25060 Amitriptyline Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
- GC52449 Spadin (trifluoroacetate salt) An inhibitor of K2P2.1/TREK1
- GC52328 KYL (trifluoroacetate salt) An EphA4 inhibitor
- GC52274 Y-33075 (hydrochloride) An inhibitor of ROCK2
- GC64554 Aloenin La aloenina (Aloenina A) es un compuesto natural que tiene potentes actividades de captaciÓn de radicales peroxilo y actividad inhibitoria moderada sobre la β-secretasa (BACE).
- GC52106 5-hydroxy Isatin An inhibitor of MAO-A
- GC52078 Galantamine (hydrobromide) An alkaloid with AChE inhibitory and nAChR potentiating activities
- GC52006 CB-096 An inhibitor of RAN translation
- GC49897 ELOVL1-22 An inhibitor of ELOVL1
- GC49829 DL-threo-β-Hydroxyaspartic Acid An EAAT inhibitor
- GC49769 β-Glucogallin A plant metabolite and an aldose reductase 2 inhibitor
- GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
- GC49573 C3 An inhibitor of MAO-B
- GC49556 Cl-Necrostatin-1 A RIPK1 inhibitor
- GC49359 IM-156 (acetate) A mitochondrial complex I inhibitor and an AMPKα activator
- GC49300 BIM-46187 (hydrochloride) An inhibitor of heterotrimeric G-protein signaling
- GC49269 Myr-ZIP A PKMζ inhibitor
- GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor
- GC49201 PF 9601N An inhibitor of MAO-B
- GC49094 CAY10781 An NRP-1/VEGF-A interaction inhibitor
- GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
- GC48814 Mesembrine La mesembrina, un alcaloide psicoactivo, es un racemato parcial en S.
- GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor
- GC48159 TFB-TBOA (hydrate) An inhibitor of EAAT1 and EAAT2
- GC47528 Ketorolac (calcium salt) El ketorolaco (RS37619) hemicÁlcico es un fÁrmaco antiinflamatorio no esteroideo (AINE) que actÚa como un inhibidor no selectivo de la COX, con IC50 de 20 nM para COX-1 y 120 nM para COX-2.
- GC47435 HPI-1 (hydrate) A Hedgehog pathway inhibitor
- GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor
- GC47314 Ethopropazine (hydrochloride) El clorhidrato de etopropazina (isotazina) es un inhibidor potente y selectivo de la BChE y un inhibidor deficiente de la AChE.
- GC47287 Eltenac Eltenac, un fÁrmaco antiinflamatorio no esteroideo (AINE), es un inhibidor de la COX.
- GC47263 Donecopride (fumarate hydrate) A 5-HT4 receptor partial agonist and AChE inhibitor
- GC47060 CAY10762 An inhibitor of MAGL
- GC47058 CAY10756 An inhibitor of ASK1
- GC47053 CAY10746 A ROCK1 and ROCK2 inhibitor
- GC46935 Bobcat 339 Bobcat 339 es un inhibidor potente y selectivo basado en citosina de la enzima TET, con IC50 de 33 μM y 73 μM para TET1 y TET2, respectivamente. Bobcat 339 es útil en el campo de la epigenética y sirve como punto de partida para nuevas terapias dirigidas a la metilación del ADN y la transcripción de genes.
- GC46897 AUTEN-99 AUTEN-99 (bromhidrato) es un nuevo inhibidor de la miotubularina fosfatasa Jumpy (también llamada MTMR14).
- GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
- GC46720 6,9-Dichloro-1,2,3,4-tetrahydroacridine A synthetic intermediate in the synthesis of AChE inhibitors
- GC46451 16F16 A PDI inhibitor
- GC46366 1,2,3,4-Tetrahydro-β-carboline A serotonin reuptake inhibitor and metabolite of tryptamine
- GC60875 GKT136901 GKT136901 es un inhibidor potente, selectivo y activo por vÍa oral de la NADPH oxidasa (NOX1/4), con Kis de 160 y 165 nM, respectivamente.
- GC60345 Sphondin Sphondin posee un efecto inhibitorio sobre el aumento inducido por IL-1β en el nivel de proteÍna COX-2 y la liberaciÓn de PGE2 en células A549 .
- GC46213 Ro 41-0960 Ro 41-0960 es un inhibidor selectivo de la catecol-O-metiltransferasa (COMT).
- GC46197 PD 90780 (hydrate) An inhibitor of NGF-p75 NGFR interactions
- GC45995 DO264 An ABHD12 inhibitor
- GC45917 Leucettine L41 La leucettina L41 es un potente inhibidor de la cinasa regulada por fosforilaciÓn de tirosina de doble especificidad 1A (DYRK1A), DYRK2, cinasa similar a CDC 1 (CLK1) y CLK3 (IC50s = 0,04, 0,035, 0,015 y 4,5 μM, respectivamente)[1 ].
- GC45911 Zopolrestat Zopolrestat (CP73850) es un potente inhibidor de la aldosa reductasa (AR) activo por vÍa oral con una IC50 de 3,1 nM.
- GC38657 Meclofenamate sodium El Ácido meclofenÁmico (meclofenamato) sÓdico es un fÁrmaco antiinflamatorio no esteroideo (AINE) aprobado para su uso en artritis (osteo y reumatoide), analgesia (dolor leve a moderado), dismenorrea y pérdida abundante de sangre menstrual (menorragia).
- GC38196 Licofelone A dual inhibitor of COX1/COX2 and 5LO
- GC38015 Eicosatetraynoic acid A nonspecific inhibitor of cyclooxygenases and lipoxygenases
- GC45579 Tiaprofenic Acid El Ácido tiaprofénico es un fÁrmaco antiinflamatorio no esteroideo (AINE) activo por vÍa oral con potencia antiinflamatoria y analgésica.
- GC45515 MX1013 MX1013 es un inhibidor dipéptido caspasa potente e irreversible con actividad antiapoptÓtica. MX1013 inhibe la caspasa 3 humana recombinante con una IC50de 30 nM.
- GC37905 Vigabatrin La vigabatrina (γ-vinil-GABA), un derivado vinÍlico del neurotransmisor inhibitorio GABA, es un inhibidor de la transaminasa GABA irreversible y activo por vÍa oral.