Pimpinellin |
| Catalog No.GC36920 |
La pimpinellin es un constituyente de Cyrtomium fortumei (J.). La pimpinellin inhibe el crecimiento de las células tumorales a través de la inducciÓn de la apoptosis de las células tumorales.
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Cas No.: 131-12-4
Sample solution is provided at 25 µL, 10mM.
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Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1].
Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1].
[1]. Yang S, et al. Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes. Chem Cent J. 2013 Feb 4;7(1):24.
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