Pimpinellin |
| Catalog No.GC36920 |
Pimpinellin은 Cyrtomium fortumei (J.)의 구성 성분입니다. Pimpinellin은 종양 세포의 세포 사멸 유도를 통해 종양 세포의 성장을 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 131-12-4
Sample solution is provided at 25 µL, 10mM.
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Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1].
Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1].
[1]. Yang S, et al. Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes. Chem Cent J. 2013 Feb 4;7(1):24.
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