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Home >> Signaling Pathways >> Immunology/Inflammation >> Innate Immunity

Innate Immunity

Products for  Innate Immunity

  1. Cat.No. Product Name Information
  2. GC18602 p38 MAPK Inhibitor IV p38 MAPK Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC50s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively. p38 MAPK Inhibitor IV Chemical Structure
  3. GC52342 P4pal10 (trifluoroacetate salt) A PAR4 and FPR2 antagonist and an FFAR2 agonist P4pal10 (trifluoroacetate salt) Chemical Structure
  4. GC44540 PAF C-16 Carboxylic Acid PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-16 Carboxylic Acid Chemical Structure
  5. GC47855 PAF C-16-d4 An internal standard for the quantification of PAF C16 PAF C-16-d4 Chemical Structure
  6. GC44541 PAF C-18 PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. PAF C-18 Chemical Structure
  7. GC41450 PAF C-18:1 PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response. PAF C-18:1 Chemical Structure
  8. GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  9. GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  10. GC49061 Pam2CSK4 (trifluoroacetate salt) A bacterial lipopeptide and TLR2 agonist Pam2CSK4 (trifluoroacetate salt) Chemical Structure
  11. GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2 PAR2 (1-6) amide (human) (trifluoroacetate salt) Chemical Structure
  12. GC44579 PCTR1 Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR1 Chemical Structure
  13. GC44580 PCTR2 Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR2 Chemical Structure
  14. GC44581 PCTR3 Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. PCTR3 Chemical Structure
  15. GC47931 PDE4B Inhibitor A PDE4B inhibitor PDE4B Inhibitor Chemical Structure
  16. GC44590 Pellitorine An amide alkaloid with diverse biological activities Pellitorine Chemical Structure
  17. GC52127 Pexiganan (acetate) Pexiganan (acetate) Chemical Structure
  18. GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (bovine) Chemical Structure
  19. GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. Phosphatidylserines (sodium salt) Chemical Structure
  20. GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor PKI (14-22) amide (myristoylated) (trifluoroacetate salt) Chemical Structure
  21. GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor Plerixafor-d4 Chemical Structure
  22. GC47964 pNPS-DHA An anti-allergic DHEA derivative pNPS-DHA Chemical Structure
  23. GC52270 Pranoprofen-13C-d3 An internal standard for the quantification of pranoprofen Pranoprofen-13C-d3 Chemical Structure
  24. GC48501 Preterramide C Preterramide C is a fungal metabolite. Preterramide C Chemical Structure
  25. GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. Prostaglandin D2 methyl ester Chemical Structure
  26. GC47988 Prostaglandin D2-d4 An internal standard for the quantification of prostaglandin D2 Prostaglandin D2-d4 Chemical Structure
  27. GC40981 Protectin D1 Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid. Protectin D1 Chemical Structure
  28. GC48993 Protectin D1-d5 An internal standard for the quantification of protectin D1 Protectin D1-d5 Chemical Structure
  29. GC44794 Pyrrophenone The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone Chemical Structure
  30. GC40004 Quinolactacin A Quinolactacin A is a TNF production inhibitor. Quinolactacin A Chemical Structure
  31. GC44802 R-8507 R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI). R-8507 Chemical Structure
  32. GC48461 rac-trans-4-hydroxy Glyburide An active metabolite of glyburide rac-trans-4-hydroxy Glyburide Chemical Structure
  33. GC48035 RCTR1 A specialized pro-resolving mediator RCTR1 Chemical Structure
  34. GC41231 Resolvin D2 methyl ester Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. Resolvin D2 methyl ester Chemical Structure
  35. GC49279 Resolvin D2 n-3 DPA A specialized pro-resolving mediator Resolvin D2 n-3 DPA Chemical Structure
  36. GC48042 Resolvin D2-d5 An internal standard for the quantification of RvD2 Resolvin D2-d5 Chemical Structure
  37. GC41232 Resolvin D3 methyl ester Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. Resolvin D3 methyl ester Chemical Structure
  38. GC44818 Resolvin D4

    Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.

     Resolvin D4 Chemical Structure
  39. GC40982 Resolvin D5

    Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

     Resolvin D5 Chemical Structure
  40. GC48972 Resolvin E2 A specialized pro-resolving mediator Resolvin E2 Chemical Structure
  41. GC48045 Resolvin E4 A specialized pro-resolving mediator Resolvin E4 Chemical Structure
  42. GC44820 Resveratrol-3-O-Sulfate (sodium salt) Resveratrol-3-O-sulfate (sodium) is the metabolite of Resveratrol. Resveratrol-3-O-Sulfate (sodium salt) Chemical Structure
  43. GC41189 Ricinelaidic Acid Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes). Ricinelaidic Acid Chemical Structure
  44. GC44839 Ridaifen-B An analog of tamoxifen Ridaifen-B Chemical Structure
  45. GC48048 Rifampicin-d3 An internal standard for the quantification of rifampicin Rifampicin-d3 Chemical Structure
  46. GC44851 Rosiglitazone (potassium salt) Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone (potassium salt) Chemical Structure
  47. GC48059 Rosiglitazone-d3 An internal standard for the quantification of rosiglitazone Rosiglitazone-d3 Chemical Structure
  48. GC41626 Sappanone A

    Sappanone A is a homoisoflavanone with strong antioxidant and anti-inflammatory activities.

     Sappanone A Chemical Structure
  49. GC46221 Seselin An angular pyranocoumarin with diverse biological activities Seselin Chemical Structure
  50. GC18821 SGA360 SGA360 is a selective modulator of the aryl hydrocarbon receptor (AhR), which is a ligand-dependent transcription factor that mediates the toxicity of certain xenobiotics and polyaromatic hydrocarbons. SGA360 Chemical Structure
  51. GC49333 SH-42 An inhibitor of DHCR24 SH-42 Chemical Structure
  52. GC49002 Sinigrin (hydrate) A glucosinolate with diverse biological activities Sinigrin (hydrate) Chemical Structure
  53. GC49049 SMU127 An agonist of TLR1/2 SMU127 Chemical Structure
  54. GC49400 SN-011 A STING antagonist SN-011 Chemical Structure
  55. GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sulfide (hydrate) Chemical Structure
  56. GC44919 SP 600125, negative control SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM. SP 600125, negative control Chemical Structure
  57. GC44930 Sphingosine (d14:1) Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. Sphingosine (d14:1) Chemical Structure
  58. GC48098 SR 12343 An IKKβ NBD mimetic SR 12343 Chemical Structure
  59. GC48099 SR 12460 An IKKβ NBD mimetic SR 12460 Chemical Structure
  60. GC45567 SR 1903   SR 1903 Chemical Structure
  61. GC61293 SR-717

    SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic, Antitumor activity.

     SR-717 Chemical Structure
  62. GC45831 SRI-011381 A TGF-β signaling activator SRI-011381 Chemical Structure
  63. GC40922 SRS11-92 SRS11-92 is a ferroptosis inhibitor and a derivative of ferrostatin-1. SRS11-92 Chemical Structure
  64. GC44948 StA-IFN-1 StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway. StA-IFN-1 Chemical Structure
  65. GC49844 Stercobilin (hydrochloride) A fecal pigment and metabolite of bilirubin Stercobilin (hydrochloride) Chemical Structure
  66. GC48109 STING Agonist 12b A STING agonist STING Agonist 12b Chemical Structure
  67. GC48110 STING Agonist 1a STING Agonist 1a (1a) is a specific stimulator of interferon genes (STING) agonist. STING Agonist 1a Chemical Structure
  68. GC45570 STING Agonist C11   STING Agonist C11 Chemical Structure
  69. GC46227 STING18 A competitive STING ligand STING18 Chemical Structure
  70. GC44956 Streptochlorin Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. Streptochlorin Chemical Structure
  71. GC52496 Sulfatide (bovine) (sodium salt) A mixture of isolated bovine sulfatides Sulfatide (bovine) (sodium salt) Chemical Structure
  72. GC44968 Sulfatides (bovine) (sodium salt) Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system. Sulfatides (bovine) (sodium salt) Chemical Structure
  73. GC18453 Sulochrin Sulochrin is a fungal metabolite produced by A. Sulochrin Chemical Structure
  74. GC48764 Sydowinin B A xanthone polyketide with immunosuppressant activity Sydowinin B Chemical Structure
  75. GC49047 T-5342126 A TLR4 antagonist T-5342126 Chemical Structure
  76. GC48447 TAS 205 An inhibitor of H-PGDS TAS 205 Chemical Structure
  77. GC44999 Tauro-α-muricholic Acid (sodium salt) Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid. Tauro-α-muricholic Acid (sodium salt) Chemical Structure
  78. GC45004 TC 14012 (trifluoroacetate salt) C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). TC 14012 (trifluoroacetate salt) Chemical Structure
  79. GC49105 Tebipenem (hydrate) A carbenapenem antibiotic Tebipenem (hydrate) Chemical Structure
  80. GC45012 Tenofovir diphosphate (sodium salt) Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). Tenofovir diphosphate (sodium salt) Chemical Structure
  81. GC49386 Tepoxalin A dual inhibitor of COX and 5-LO Tepoxalin Chemical Structure
  82. GC40627 tetranor-Misoprostol tetranor-Misoprostol is a metabolite of misoprostol. tetranor-Misoprostol Chemical Structure
  83. GC19001 Tetromycin B Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively. Tetromycin B Chemical Structure
  84. GC45030 TG6-129 Prostaglandin E2 evokes distinct responses through four different 'E prostanoid' (EP) receptors. TG6-129 Chemical Structure
  85. GC48163 Theophylline-d6 An internal standard for the quantification of theophylline Theophylline-d6 Chemical Structure
  86. GC49503 Thujopsene A sesquiterpene with diverse biological activities Thujopsene Chemical Structure
  87. GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) Chemical Structure
  88. GC49062 Tiopronin-d3 An internal standard for the quantification of tiopronin Tiopronin-d3 Chemical Structure
  89. GC45057 TIQ-A Poly(ADP-ribose) polymerase 1 (PARP1) is a critical DNA repair enzyme involved in DNA single-strand break repair via the base excision repair pathway. TIQ-A Chemical Structure
  90. GC45965 Tolfenamic Acid-d4 An internal standard for the quantification of tolfenamic acid Tolfenamic Acid-d4 Chemical Structure
  91. GC45063 Toll-Like Receptor 7 Ligand II Toll-Like Receptor 7 Ligand II (CL-087) is a potent, oral actively TLR7 agonist. Toll-Like Receptor 7 Ligand II Chemical Structure
  92. GC49150 Tpl2 Kinase Inhibitor (hydrochloride) A Tpl2 inhibitor Tpl2 Kinase Inhibitor (hydrochloride) Chemical Structure
  93. GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (diethanolamine salt) Chemical Structure
  94. GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases Trifluoroacetyl Tripeptide-2 (acetate) Chemical Structure
  95. GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline Trigonelline-d3 (chloride) Chemical Structure
  96. GC41638 TSI-01

    Platelet-activating factor (PAF) is a pro-inflammatory phospholipid mediator that is rapidly synthesized by lyso-PAF acetyltransferase (lyso-PAFAT) in response to extracellular stimuli.

     TSI-01 Chemical Structure
  97. GC52412 TT-232 (trifluoroacetate salt) A synthetic peptide derivative of somatostatin TT-232 (trifluoroacetate salt) Chemical Structure
  98. GC49099 Tuftsin (human) (trifluoroacetate salt) A phagocytosis-stimulating peptide Tuftsin (human) (trifluoroacetate salt) Chemical Structure
  99. GC49835 Tumulosic Acid Tumulosic Acid, a triterpenoid, inhibits KLK5 protease activity (IC50= 14.84 μM). Tumulosic Acid Chemical Structure
  100. GC48987 UDP (sodium salt hydrate) An agonist of P2Y6 UDP (sodium salt hydrate) Chemical Structure
  101. GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide Vimentin (139-159)-biotin Peptide Chemical Structure

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