Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
منتجات لـ نبسب؛ Metabolism
- القط. رقم اسم المنتج بيانات
- GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone
- GC49176 5β-Tetrahydrocortisol An endogenous metabolite of cortisol
- GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam
- GC49499 5(Z)-Dodecenoic Acid 5 (Z) -Dodecenoic Acid هو مستقلب داخلي له أنشطة مثبطة ضد COX-I و COX-II.
-
GC18542
5,6-dihydro-5-Fluorouracil
5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).
- GC18466 5,6-epoxy-13-cis Retinoic Acid 5,6-epoxy-13-cis Retinoic acid is a metabolite of 13-cis retinoic acid.
- GC13319 5,8,11-Eicosatriynoic Acid nonselective inhibitor of lipoxygenases (12-LO)
- GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols
- GC63358 5-Aminosalicylic Acid-D3 hydrochloride
- GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid
- GC49827 5-Androstenetriol An active metabolite of DHEA
- GC49877 5-bromo-3-indolyl-β-D-Galactopyranoside 5-bromo-3-indolyl-β ؛ -D-Galactopyranoside (Bluo-Gal) عبارة عن ركيزة كروموجينية للكشف عن β ؛ نشاط د-غالاكتوزيداز.
- GC49655 5-hydroxy Buspirone A metabolite of buspirone
- GC42546 5-hydroxy Diclofenac 5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4.
- GC49119 5-hydroxy Flunixin A metabolite of flunixin
- GC49315 5-hydroxy Indomethacin A metabolite of indomethacin
-
GC41312
5-hydroxy Omeprazole
5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump.
- GC12829 5-hydroxy Tryptophol 5-هيدروكسي التربتوفول هو مستقلب سيروتونين للثدييات ، يعمل كعلامة على استهلاك الكحول الحاد.
- GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine.
- GC42551 5-hydroxymethyl Tolterodine (formate) 5-hydroxymethyl Tolterodine is an active metabolite of the muscarinic acetylcholine receptor antagonists tolterodine and fesoterodine.
- GN10241 5-Methoxypsoralen
- GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid
- GC41310 5-Octyl-α-ketoglutarate In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.
- GC46713 5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate) An intermediate in several biochemical pathways
- GC11101 5-R-Rivaroxaban
- GC42586 6α-hydroxy Paclitaxel 6α ؛ -هيدروكسي باكليتاكسيل هو مستقلب أساسي للباكليتاكسيل. 6α ؛ - يحتفظ هيدروكسي باكليتاكسيل بتأثير يعتمد على الوقت على بولي ببتيدات نقل الأنيون العضوي 1B1 / SLCO1B1 (OATP1B1) مع فعالية تثبيط مماثلة لباكليتاكسيل ، في حين أنه لم يعد يظهر تثبيطًا معتمدًا على الوقت لـ OATP1B3. 6α ؛ -يمكن استخدام هيدروكسي باكليتاكسيل لأبحاث السرطان.
- GC49676 6β-hydroxy Budesonide A metabolite of budesonide
- GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone
- GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone
- GC19536 6'-Sialyllactose Sodium Salt 6' ؛ -سياللاكتوز (صوديوم) ، وهو أحد السكريات السائدة في الحليب ، يقلل من استيعاب الزائفة الزنجارية في الخلايا الرئوية البشرية.
- GC52056 6(Z),9(Z),12(Z),15(Z)-Hexadecatetraenoic Acid ethyl ester 6 (Z) ، 9 (Z) ، 12 (Z) ، 15 (Z) -Hexadecatetraenoic Acid ethyl ester هو n-1PUFA نشط عن طريق الفم.
- GC11864 6,7-dihydroxy Bergamottin potent inhibitor of CYP3A4
- GC10868 6,7-Dimethyltetrahydropterin (hydrochloride) GTP cyclohydrolase I inhibitor
- GC10462 6-Aminonicotinamide 6-أمينونيكوتيناميد ، أحد مضادات الأيض القوية للنيكوتيناميد ، هو مثبط إنزيم NADP المعتمد على إنزيم الجلوكوز 6 فوسفات ديهيدروجينيز (G6PD) (Ki =0.46 ميكرومتر)6-أمينونيكوتيناميد يتداخل مع تحلل السكر ، مما يؤدي إلى استنفاد ATP ويتآزر مع أدوية العلاج الكيميائي المتشابك للحمض النووي ، مثل سيسبلاتين ، في قتل الخلايا السرطانية
- GC46722 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) A β-glucuronidase chromogenic substrate
- GC18632 6-hydroxy Bexarotene 6-hydroxy Bexarotene is an oxidative metabolite of bexarotene , a high-affinity ligand for retinoid X receptors (RXRs).
-
GC42580
6-hydroxy Chlorzoxazone
6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.
- GC49183 6-hydroxy Etodolac A metabolite of etodolac
- GC18219 6-hydroxy Warfarin 6-hydroxy Warfarin is a metabolite of (+)-warfarin , which is a weaker vitamin K antagonist than (-)-warfarin .
- GC49429 6-keto Lithocholic Acid A metabolite of lithocholic acid
- GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine
- GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP
- GC18870 6-NBDG 6-NBDG هو نظير جلوكوز فلوري ، يمكن استخدامه للتصوير الفلوري ومراقبة نقل الجلوكوز وامتصاصه.
- GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin
- GC42584 6-O-desmethyl Donepezil 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil.
- GC46726 6-O-Sulfo-β-cyclodextrin (sodium salt) A sulfated cyclodextrin
- GC18335 6β-hydroxy Dexamethasone 6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.
- GC49206 7α-hydroxy Dehydroepiandrosterone An active metabolite of dehydroepiandrosterone
- GC49298 7α-Thiomethylspironolactone A major metabolite of spironolactone
- GC49391 7α-Thiospironolactone An active metabolite of spironolactone
- GC40201 7β-hydroxy Cholesterol-d7 7β-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7β-hydroxy cholesterol by GC- or LC-MS.
- GC42595 7(Z),11(Z)-Heptacosadiene The mating and social behaviors of insects are largely orchestrated by a suite of volatile cuticular hydrocarbon pheromones.
- GC42596 7(Z),11(Z)-Nonacosadiene 7 (Z) ، 11 (Z) -Nonacosadiene هو فرمون ذبابة الفاكهة السوداء من مشتق رباعي هيدروفيريدين.
- GC42597 7(Z),11(Z)-Pentacosadiene Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones.
- GC42598 7(Z)-Pentacosene 7(Z)-Pentacosene is an unsaturated cuticular hydrocarbon that acts as a contact sex pheromone in fruit flies.
- GC42599 7(Z)-Tricosene 7(Z)-Tricosene is an unsaturated cuticular hydrocarbon that acts as a pheromone in some insects, including Drosophila.
- GC46080 7,3',4'-Trihydroxyflavone 7،3'؛، 4'؛ -Trihydroxyflavone مركب فلافونويد aglycon معزول عن قرون الفاصوليا العريضة.
- GC10533 7,8-dihydro-L-Biopterin 7،8-ديهيدرو- L- بيوبترين هو منتج أكسدة لرباعي هيدروبيوبترين
- GC46735 7-Biopterin A pterin
- GC46736 7-Bromoheptanoic Acid A building block
-
GC46242
7-dehydro Cholesterol-d7
7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol
- GC13784 7-Ethoxyresorufin 7-Ethoxyresorufin (Resorufin ethyl ether) عبارة عن ركيزة قياس الفلور ومثبط تنافسي للسيتوكروم P450 ، وخاصة CYP1A1
- GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine
- GC42606 7-hydroxy Coumarin Glucuronide (sodium salt) 7-hydroxy Coumarin glucuronide is a 7-hydroxy coumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumarin metabolism.
- GC42607 7-hydroxy Coumarin sulfate (potassium salt) 7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.
- GC49051 7-hydroxy Methotrexate 7-هيدروكسي الميثوتريكسات هو مستقلب رئيسي للميثوتريكسات
-
GC42608
7-hydroxy Methotrexate (sodium salt)
7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.
- GC10565 7-hydroxycoumarinyl Arachidonate 7-Hydroxycoumarinyl arachidonate (7-HCA) عبارة عن ركيزة فلوروجينية من فوسفوليباز العصاري الخلوي A2 (PLA2)
- GC42611 7-hydroxycoumarinyl-γ-Linolenate 7-hydroxycoumarinyl-γ ؛ -Linolenate عبارة عن ركيزة فلوروجينية فوسفوليباز عصاري خلوي A2 (cPLA2).
- GC65409 7-Methylcoumarin 7-ميثيل كومارين ، وهو الكومارين ، يُظهر نشاطًا قويًا في حماية الكبد وتأثيرًا قويًا مضادًا للأكسدة
- GC18284 7-Methyluric Acid 7-Methyluric acid is a methylated purine and uric acid derivative.
- GC42620 8-Aminopyrene-1,3,6-trisulfonic Acid (sodium salt) 8-أمينوبيرين-1،3،6-تريسولفونيك أسيد (ملح الصوديوم) هو صبغة أنيونية مشعة قابلة للذوبان في الماء.
- GC52126 8-chloro Caffeine
- GC35201 8-Geranyloxypsoralen 8-Geranyloxypsoralen هو فورانوكومارين معزول من الجريب فروت ، ويعمل كمثبط قوي لـ P450 3A4 (CYP3A4) مع IC50 من 3.93 ميكرومتر
- GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
- GC42626 8-hydroxy Efavirenz 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz.
- GC18654 8-hydroxy Loxapine 8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2.
- GC49544 8-hydroxy Mirtazapine A metabolite of mirtazapine
- GN10330 8-Methoxypsoralen
- GC42633 9(E)-Erythromycin A oxime (9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .
- GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid
- GC45366 9(Z)-Pentacosene
- GC42641 9(Z)-Tricosene (9Z)-Tricosene is a pheromone released by insects, including D.
- GC40338 9-deoxy-9-methylene Prostaglandin E2 9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2.
- GC40470 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo.
- GC42649 9-Nitrooleate Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate, cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules.
- GC42651 9-oxo-10(E),12(E)-Octadecadienoic Acid 9-oxo-10(E),12(E)-Octadecadienoic acid (9-oxoODA) is a natural agonist, abundant in tomatoes, that activates PPARα at 10-20 μM.
- GC46761 9-Oxononanoic Acid An oxidized fatty acid
- GC50419 A 33 A 33 هو مثبط PDE4B نشط عن طريق الفم وانتقائي مع IC50 من 15 نانومتر.
- GC13262 A-771726 dihydroorotate dehydrogenase inhibitor
- GC46765 A6770 A6770 هو مثبط لياز (S1PL) فعال عن طريق الفم وفعال من سفينجوزين 1-فوسفات (S1P)
- GC15614 A922500 A diacylglycerol acyltransferase 1 inhibitor
- GC15921 A939572 A939572 هو مثبط قوي ومتوفر حيوياً لـ stearoyl-CoA desaturase1 (SCD1) بقيم IC50 <4 نانومتر و 37 نانومتر لـ mSCD1 و hSCD1 ، على التوالي
- GC31355 AA26-9 AA26-9 هو مثبط هيدرولاز قوي وواسع الطيف
-
GC16115
AACOCF3
مثبط لـ cPLA2 / تحلل الأنانداميد / FAAH
- GC42667 Abacavir Carboxylate Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir.
- GC46768 Abaloparatide (acetate) A synthetic derivative of PTHrP and an agonist of PTHR1
- GC17645 Abiraterone A CYP17A1 inhibitor and an active metabolite of abiraterone acetate
- GC11108 Abiraterone acetate A CYP17A1 inhibitor
- GC64010 Abiraterone decanoate ديكانوات ابيراتيرون هو دواء مساعد فعال لأبراتيرونيوفر Abiraterone decanoate إطلاقًا مضبوطًا من Abiraterone وتثبيط CYP17 طويل المفعول مع التوصيل العضلي (IM)