(±)5-HEPE |
| Catalog No.GC40364 |
(±)5-HEPE is produced by non-enzymatic oxidation of EPA.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 83952-40-3
Sample solution is provided at 25 µL, 10mM.
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(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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