BI-9627 |
| Catalog No.GC34492 |
Le BI-9627 est un puissant inhibiteur de l'isoforme 1 (NHE1) de l'échangeur sodium-hydrogène, avec des IC50 de 6 et 31 nM dans les tests de récupération du pH intracellulaire (pHi) et de gonflement des plaquettes humaines, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1204329-34-9
Sample solution is provided at 25 µL, 10mM.
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BI-9627 is a sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with an EC50 of 31 nM[1]. EC50: 31 nM (Sodium-hydrogen exchanger isoform 1)[1]
[1]. Huber JD, et al. Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitableprofile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. J Med Chem. 2012 Aug 23;55(16):7114-40.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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