BI-9627 |
| Katalog-Nr.GC34492 |
BI-9627 ist ein potenter Inhibitor der Natrium-Wasserstoff-Austauscher-Isoform 1 (NHE1) mit IC50-Werten von 6 und 31 nM in intrazellulÄren pH-Erholungs- (pHi) bzw. Assays zur Schwellung menschlicher BlutplÄttchen.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1204329-34-9
Sample solution is provided at 25 µL, 10mM.
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BI-9627 is a sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with an EC50 of 31 nM[1]. EC50: 31 nM (Sodium-hydrogen exchanger isoform 1)[1]
[1]. Huber JD, et al. Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitableprofile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. J Med Chem. 2012 Aug 23;55(16):7114-40.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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