CM10 |
| Catalog No.GC39215 |
Le CM10 est un inhibiteur puissant et sélectif de la famille des aldéhydes déshydrogénases 1A (ALDH1A), avec des CI50 de 1700, 740 et 640 nM pour ALDH1A1, ALDH1A2 et ALDH1A3, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 692269-09-3
Sample solution is provided at 25 µL, 10mM.
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CM10 is a potent and selective aldehyde dehydrogenase 1A family inhibitor (ALDH1Ai), with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity[1].
[1]. Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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