CM10 |
| Catalog No.GC39215 |
CM10은 ALDH1A1, ALDH1A2 및 ALDH1A3에 대해 IC50이 각각 1700, 740 및 640nM인 강력하고 선택적인 알데히드 탈수소효소 1A(ALDH1A) 계열 억제제입니다.
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Cas No.: 692269-09-3
Sample solution is provided at 25 µL, 10mM.
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CM10 is a potent and selective aldehyde dehydrogenase 1A family inhibitor (ALDH1Ai), with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity[1].
[1]. Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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