CM10 |
| カタログ番号GC39215 |
CM10 は強力で選択的なアルデヒド脱水素酵素 1A (ALDH1A) ファミリー阻害剤であり、ALDH1A1、ALDH1A2、および ALDH1A3 の IC50 はそれぞれ 1700、740、および 640 nM です。
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Cas No.: 692269-09-3
Sample solution is provided at 25 µL, 10mM.
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CM10 is a potent and selective aldehyde dehydrogenase 1A family inhibitor (ALDH1Ai), with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity[1].
[1]. Chefetz I, et al. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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