FC131 TFA |
Catalog No.GC36033 |
FC131 TFA est un antagoniste de CXCR4, inhibe la liaison de [125I]-SDF-1 À CXCR4, avec une IC50 de 4,5 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity[1]. IC50: 4.5 nM ([125I]-SDF-1-CXCR4)[1]HIV-1[1]
[1]. Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
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