FC131 TFA |
Katalog-Nr.GC36033 |
FC131 TFA ist ein CXCR4-Antagonist, hemmt die Bindung von [125I]-SDF-1 an CXCR4 mit einem IC50 von 4,5 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity[1]. IC50: 4.5 nM ([125I]-SDF-1-CXCR4)[1]HIV-1[1]
[1]. Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
Average Rating: 5
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