FC131 TFA |
| カタログ番号GC36033 |
FC131 TFA は CXCR4 アンタゴニストであり、[125I]-SDF-1 の CXCR4 への結合を 4.5 nM の IC50 で阻害します。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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FC131 TFA is a CXCR4 antagonist, inhibits [125I]-SDF-1 binding to CXCR4, with an IC50 of 4.5 nM. Anti-HIV activity[1]. IC50: 4.5 nM ([125I]-SDF-1-CXCR4)[1]HIV-1[1]
[1]. Tamamura H, et al. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131. J Med Chem. 2005 Jan 27;48(2):380-91.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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