Ingenol ((-)-Ingenol) |
| Catalog No.GC32870 |
Ingenol ((-)-Ingenol) est un activateur PKC, avec un Ki de 30 μM, avec une activité antitumorale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 30220-46-3
Sample solution is provided at 25 µL, 10mM.
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Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1].
[1]. Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.
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