Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) (Synonyms: Lys-Nε-MCC-DM1) |
Catalog No.GC33500 |
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) (Lys-Nε-MCC-DM1) est un composant de charge utile de liaison qui a le potentiel d'inhiber la polymérisation de la tubuline.Lys-SMCC-DM1 (Lys-Nε -MCC-DM1) est le métabolite actif du T-DM1. T-DM1 est un ADC ciblant le récepteur 2 du facteur de croissance épidermique humain (HER2) avec un inhibiteur de polymérisation de la tubuline DM1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1281816-04-3
Sample solution is provided at 25 µL, 10mM.
Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is an FDA approved HER2-targeting ADC.
[1]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
Average Rating: 5
(Based on Reviews and 1 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *