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Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) (Synonyms: Lys-Nε-MCC-DM1)

Catalog No.GC33500

Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) (Lys-Nε-MCC-DM1) est un composant de charge utile de liaison qui a le potentiel d'inhiber la polymérisation de la tubuline.Lys-SMCC-DM1 (Lys-Nε -MCC-DM1) est le métabolite actif du T-DM1. T-DM1 est un ADC ciblant le récepteur 2 du facteur de croissance épidermique humain (HER2) avec un inhibiteur de polymérisation de la tubuline DM1.

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Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) Chemical Structure

Cas No.: 1281816-04-3

Taille Prix Stock Qté
10mM (in 1mL DMSO)
1 618,00 $US
En stock
1mg
321,00 $US
En stock
5mg
873,00 $US
En stock
10mg
1 333,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is an FDA approved HER2-targeting ADC.

[1]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

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