13,14-dihydro-15-keto-tetranor Prostaglandin E2 (Synonyms: 13,14-dihydro-15-keto-tetranor PGE2) |
カタログ番号GC40626 |
PGE2を含むいくつかのプロスタグランジン(PG)に共通する代謝経路は、C-13とC-14の二重結合の還元と、C-15のヒドロキシル基の酸化によって、13,14-ジヒドロ-15-ケトPGが生成されることを特徴としています。
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Cas No.: 20675-85-8
Sample solution is provided at 25 µL, 10mM.
A common metabolic pathway for several prostaglandins (PG), including PGE2, involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the α-terminus and oxidation of the terminal ω-carbon produces the abundant urinary metabolites, including tetranor PGEM. 13,14-dihydro-15-keto tetranor PGE2 is a potential metabolite of PGE2. It would be produced from the known metabolite 13,14-dihydro-15-keto PGE2 , which is known to have a short plasma half-life.
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