13,14-dihydro-15-keto-tetranor Prostaglandin F1α (Synonyms: 5β, 7αdihydroxy11ketotetranorProstanoic Acid, 9β13,14dihydro15ketotetranor Prostaglandin F1α, 9β,11αdihydroxy15oxo2,3,4,5tetranorProstanoic Acid) |
カタログ番号GC41903
One-Click Copy Product Info
|
Fシリーズプロスタグランジン（PG）の代謝は、一般的にC-13とC-14の二重結合の還元と、C-15のヒドロキシル基の酸化から始まり、13,14-ジヒドロ-15-ケトPGを生成します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 24379-94-0
Sample solution is provided at 25 µL, 10mM.
_1-3.$$$39978408@51.jpg');)
_1-9.$$$38538795@65.jpg');)
_1-9.$$$39112701@51.jpg');)
_1-7.$$$37316672@70.jpg');)
_366-372.$$$36198801@70.jpg');)
.$$$38565142@65.jpg');)
_1867-1883.$$$33248023@67.jpg');)
_eads6055.$$$39977546@45.jpg');)
_eadm9805.$$$40080571@45.jpg');)
_eadj3020.$$$39666821@45.jpg');)
_1-20.$$$39757301@28.jpg');)
_1-24.$$$38898113@28.jpg');)
_273-287.$$$36806353@46.jpg');)
_1-16.$$$37156877@44.jpg');)
_1-19.$$$37460805@44.jpg');)
_1291-1307.$$$34518654@46.jpg');)
The metabolism of F series prostaglandins (PGs), including PGF1α and PGF2α, commonly begins with the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the α-terminus and oxidation of the terminal ω carbon produces the abundant urinary metabolites, including tetranor-PGFM. 13,14-dihydro-15-keto tetranor PGF1α is a potential metabolite of either PGF1α or PGF2α and likely precursor to tetranor-PGFM.
| Cas No. | 24379-94-0 | SDF | |
| 同義語 | 5β, 7αdihydroxy11ketotetranorProstanoic Acid, 9β13,14dihydro15ketotetranor Prostaglandin F1α, 9β,11αdihydroxy15oxo2,3,4,5tetranorProstanoic Acid | ||
| Canonical SMILES | O[C@H]1[C@H](CCC(CCCCC)=O)[C@@H](CCC(O)=O)[C@@H](O)C1 | ||
| Formula | C16H28O5 | M.Wt | 300.4 |
| 溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.3289 mL | 16.6445 mL | 33.2889 mL |
| 5 mM | 665.8 μL | 3.3289 mL | 6.6578 mL |
| 10 mM | 332.9 μL | 1.6644 mL | 3.3289 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solution in ethanol
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)