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(2-Pyridyldithio)-PEG4-propargyl

カタログ番号GC65337

(2-ピリジルジチオ)-PEG4-プロパルギルは、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーです。

Products are for research use only. Not for human use. We do not sell to patients.

(2-Pyridyldithio)-PEG4-propargyl 化学構造

Cas No.: 2170240-99-8

サイズ 価格 在庫数 個数
5mg
$37.80
在庫あり
10mg
$61.20
在庫あり
50mg
$117.00
在庫あり
100mg
$216.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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