3'-Azido-3'-deoxy-5-methylcytidine |
カタログ番号GC65085 |
3'-アジド-3'-デオキシ-5-メチルシチジン (CS-92) は、MCF-7 細胞で 43.5 μM の CC50 を持つ強力な異種向性マウス白血病関連レトロウイルス (XMRV) 阻害剤です。
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Cas No.: 1282040-14-5
Sample solution is provided at 25 µL, 10mM.
3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 μM in peripheral blood mononuclear (PBM) cells[1].
[1]. Singh IR, et al. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One. 2010 Apr 1;5(4):e9948.
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