Avermectin B1 (Synonyms: Avermectin B1, Avermectin B1a (~80%) and Avermectin B1b (~20%) Mixture, MK-936, Rustomectin) |
カタログ番号GC11081
One-Click Copy Product Info
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昆虫殺虫剤と寄生虫駆除薬
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71751-41-2
Sample solution is provided at 25 µL, 10mM.
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. IC50 Value: N/ATarget: AntiparasiticAvermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium.
References:
[1]. Mogg TD, Pollitt CC, Willmore JP, Thompson H.Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria.Aust Vet J. 1990 Nov;67(11):399-401.
[2]. De Chaneet GC, Casey R, Dixon FF, Besier RB, Mitchell RK.Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle.Aust Vet J. 1988 Mar;65(3):85-6.
[3]. Seaman JT, Eagleson JS, Carrigan MJ, Webb RF.Avermectin B1 toxicity in a herd of Murray Grey cattle.Aust Vet J. 1987 Sep;64(9):284-5.
[4]. Murty US, Jyothi KN, Jamil K.Effect of avermectin B1 (L-676) a metabolite from Streptomyces avermilitis on immatures of Culex quinquefasciatus.Indian J Med Res. 1987 May;85:539-41.
[5]. Parrish MD, Roberts RB.Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).J Econ Entomol. 1984 Jun;77(3):769-72.
| Cas No. | 71751-41-2 | SDF | |
| 同義語 | Avermectin B1, Avermectin B1a (~80%) and Avermectin B1b (~20%) Mixture, MK-936, Rustomectin | ||
| Canonical SMILES | CCC(C1C(C)C=CC2(CC3CC(C/C=C(C)/C(OC4CC(OC)C(OC5CC(OC)C(O)C(C)O5)C(C)O4)C(C)/C=C/C=C6COC7C\6(O)C(C(O3)=O)C=C(C)C7O)O2)O1)C | ||
| Formula | C48H72O14 | M.Wt | 873.08 |
| 溶解度 | DMSO : 100mg/mL | Storage | 4°C, away from moisture and light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.1454 mL | 5.7269 mL | 11.4537 mL |
| 5 mM | 229.1 μL | 1.1454 mL | 2.2907 mL |
| 10 mM | 114.5 μL | 572.7 μL | 1.1454 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)