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AZD7624

カタログ番号GC31924

AZD7624 は、強力な抗炎症作用を持つ吸入 p38 阻害剤です。

Products are for research use only. Not for human use. We do not sell to patients.

AZD7624 化学構造

Cas No.: 1095004-78-6

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.

AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50u of 8.4, 8.7, and 9.0[1].

[1]. Pehrson R, et al. AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure. J Pharmacol Exp Ther. 2018 Jun;365(3):567-572.

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Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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