C12 1-Deoxyceramide (m18:1/12:0) (Synonyms: C12:0 1-Deoxyceramide, C12:0 Ceramide (m18:1/12:0), Cer(m18:1/12:0), N-Dodecanoyl-1-deoxy-4,5-dihydro-Sphingosine) |
| カタログ番号GC46974 |
中鎖非典型セラミド
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1246298-54-3
Sample solution is provided at 25 µL, 10mM.
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C12 1-Deoxyceramide (m18:1/12:0) is a medium-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2
1.Steiner, R., Saied, E.M., Othman, A., et al.Elucidating the chemical structure of native 1-deoxysphingosineJ. Lipid Res.57(7)1194-1203(2016) 2.Alecu, I., Othman, A., Penno, A., et al.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathwayJ. Lipid Res.58(1)60-71(2017)
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