C6 L-threo Ceramide (d18:1/6:0) (Synonyms: L-threo Cer(d18:1/6:0), L-threo Ceramide (d18:1/6:0), N-hexanoyl-L-threo-Sphingosine) |
| カタログ番号GC40690 |
C6 L-threo セラミド (d18:1/6:0) は、生理活性スフィンゴ脂質であり、天然に存在するセラミドの細胞透過性類似体です。
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Cas No.: 189894-80-2
Sample solution is provided at 25 µL, 10mM.
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C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 μM.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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