Cyclic MKEY TFA |
| カタログ番号GC35778 |
Cyclic MKEY TFA は、CXCL4-CCL5 ヘテロ二量体形成の合成環状ペプチド阻害剤であり、炎症を媒介することによってアテローム性動脈硬化症および大動脈瘤形成から保護します。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Cyclic MKEY TFA is a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, which protects against atherosclerosis and aortic aneurysm formation by mediating inflammation. Cyclic MKEY TFA also protects against stroke-induced brain injury in mice[1][2]. CXCL4-CCL5[1]
[1]. Fan Y,et al. MKEY, a Peptide Inhibitor of CXCL4-CCL5 Heterodimer Formation, Protects Against Stroke in Mice. J Am Heart Assoc. 2016 Sep 15;5(9). pii: e003615. [2]. Iida Y, et al. Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):718-26.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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