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[Nle4,D-Phe7]-α-MSH (trifluoroacetate salt)

カタログ番号GC41745

[Nle4,D-Phe7]-α-MSHは、α-メラノサイト刺激ホルモン(α-MSH)の合成アナログです。

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[Nle4,D-Phe7]-α-MSH (trifluoroacetate salt) 化学構造

サイズ 価格 在庫数 個数
1mg
$231.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-melanocyte stimulating hormone (α-MSH). It is 26-fold more potent than α-MSH at inducing adenylate cyclase activity in mouse melanoma cells in vitro. [Nle4,D-Phe7]-α-MSH also induces tyrosinase activity in a time-dependent manner in mouse melanoma cells. In vivo, [Nle4,D-Phe7]-α-MSH (1.8 μg/g) induces long-term skin darkening in R. pipiens (frogs). Formulations containing [Nle4,D-Phe7]-α-MSH have been used to induce melanogenesis in patients with erythropoietic protoporphyria.

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