5-methoxy Methylone (hydrochloride)

Methylone is a β-ketone analog of 3,4-methylenedioxymethamphetamine (3,4-MDMA) that has been detected in products marketed as bath salts, plant food, and tablets.1,2 Similar to 3,4-MDMA, it acts on components of the monoaminergic systems.3,4,5 5-methoxy Methylone is a cathinone derivative that bears a methoxy group similar to various tryptamine analogs including 5-methoxy MiPT , which are known to potently inhibit monoamine transport function.5 The pharmacological and toxicological properties of this compound are not known. This product is intended for forensic and research purposes.

References
1. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan. Leg. Med. (Tokyo) 13(3), 109-115 (2011).
2. Bossong, M.G., Van Dijk, J.P., and Niesink, R.J. Methylone and mCPP, two new drugs of abuse• Addict. Biol. 10(4), 321-323 (2005).
3. Cozzi, N.V., Sievert, M.K., Shulgin, A.T., et al. Inhibition of plasma membrane monoamine transporters by β-ketoamphetamines. European Journal of Pharmacology 381(1), 63-69 (1999).
4. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).
5. Sogawa, C., Sogawa, N., Ohyama, K., et al. Methylone and monoamine transporters: Correlation with toxicity. Curr.Neuropharmacol. 9(1), 58-62 (2011).