Succinic anhydride |
| カタログ番号GC38239 |
無水コハク酸は環状無水物であり、特許 WO2009064913A1 から抽出された切断不可能な ADC リンカーです。無水コハク酸は、特許の化合物４と反応して、プロドラッグを標的ポリペプチドのアミンまたはヒドロキシ１基に結合することができる。
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Cas No.: 108-30-5
Sample solution is provided at 25 µL, 10mM.
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Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide[1].
[1]. Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1.
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