Autotaxin-IN-3 |
| カタログ番号GC38890 |
Autotaxin-IN-3 は、特許 WO2018212534A1 に由来する化合物 33 で、IC50 が 2.4 nM の Autotaxin(ATX) 阻害剤です。
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Cas No.: 2156655-68-2
Sample solution is provided at 25 µL, 10mM.
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Autotaxin-IN-3 is a Autotaxin(ATX) inhibitor with an IC50 of 2.4 nM, compound 33, sourced from patent WO2018212534A1[1].
Autotaxin is an enzyme which is responsible for the increase in lysophosphatidic acid in ascites and plasma, and it is a secretory enzyme important for converting lysophosphatidylchloine (LPC) into lysophosphatidic acid (LPA) as a bioactive signaling molecule[1].
[1]. LEE, Dae Yon, et al. NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME. Patent O2018212534A1
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