CID44216842 (Synonyms: Cdc42-IN-1) |
| カタログ番号GC39810 |
CID44216842 (Cdc42-IN-1) は、強力な Cdc42 選択的グアニン ヌクレオチド結合リード阻害剤です。 Cdc42 WT および Cdc42Q61L 変異体の EC50 は、GTP 結合アッセイでそれぞれ 1.0 および 1.2 μM です。 Cdc42 WT および Cdc42Q61L 変異体の EC50 は、GDP 結合アッセイでそれぞれ 0.3 および 0.5 μM です。分子プローブとして使用します。
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Cas No.: 1222513-26-9
Sample solution is provided at 25 µL, 10mM.
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CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].
[1]. Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.
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