FIT-039 |
| カタログ番号GC39811 |
FIT-039 は、CKD9/サイクリン T1 に対して 5.8 μM の IC50 を持つ、選択的、ATP 競合的、経口的に活性な CDK9 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1113044-49-7
Sample solution is provided at 25 µL, 10mM.
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FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
[1]. Makoto Yamamoto, et al. CDK9 Inhibitor FIT-039 Prevents Replication of Multiple DNA Viruses. J Clin Invest. 2014 Aug;124(8):3479-88.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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