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Dibenzoyl Thiamine (Bentiamine)

カタログ番号GC30576

チアミンの誘導体であるジベンゾイルチアミン(ベンチアミン)(ベンチアミン)は、体内に急速に吸収され、チアミンに変換されます。

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Dibenzoyl Thiamine (Bentiamine) 化学構造

Cas No.: 299-88-7

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$50.00
在庫あり
100mg
$46.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

Dibenzoyl Thiamine (Bentiamine), a derivative of thiamine, is rapidly absorbed into the body and converted to thiamine.

Dibenzoyl Thiamine is a thiol-type thiamine composed of thiamine and benzoic acid. It is not decomposed by aneurinase (thiamine-decomposing enzyme), making it more suitable for food processing than thiamine hydrochloride[1].

A chronic toxicity study in male Wistar rats for 6 months at dietary levels of up to 1000 ppm, shows Dibenzoyl Thiamine to be without specific toxic effects. A teratogenicity study in rats show Dibenzoyl Thiamine to be without embryotoxic or teratogenic effects. Tests for mutagenicity in bacterial systems, in the dominant lethal assay and in an in vivo cytogenetics test show Dibenzoyl Thiamine to be without mutagenic. Dibenzoyl Thiamine is metabolised to Vitamin Br and benzoic acid, and the benzoic acid moiety is almost quantitatively excreted in the urine, as hippuric acid[1].

[1]. Heywood R, et al. Tumorigenic and toxic effect of O,S-dibenzoyl thiamine hydrochloride in prolonged dietaryadministration to rats. Toxicol Lett. 1985 Jul;26(1):53-8.

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