(R)-(-)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide |
| カタログ番号GC41705 |
N-アシルエタノールアミン（NAE）には、関連するアシル基に強く影響を受ける多様な生物学的作用があります。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Docosahexaenoyl ethanolamide (DHEA) has potential signaling roles in cancer, inflammation, and neurological development and functioning. At least some of DHEA's effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists and voltage-gated K+ channel blockers. (R)-(-)-Docosahexaenyl-2'-hydroxy-1'-propylamide is a homolog of DHEA, characterized by the addition of an (R)-β-methyl group at the terminal ethanolamine carbon. A similar modification of arachidonoyl ethanolamide to produce R-2 methanandamide imparts diminished affinity for the CB receptor as well as reduced metabolic stability. The physiological actions of this compound have not been evaluated.
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