1-Aminodecylidene bis-Phosphonic Acid (sodium salt) |
カタログ番号GC41985 |
1-アミノデシルイデンビスホスホン酸は、酸性スフィンゴミエリナーゼの強力な阻害剤です(IC50 = 20 nM)。
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Sample solution is provided at 25 µL, 10mM.
1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 μM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone in HepG2 cells.
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