Ac-IEPD-AMC (trifluoroacetate salt) (Synonyms: Acetyl-Ile-Glu-Pro-Asp-7-amino-4-Methylcoumarin, Ac-Ile-Glu-Pro-Asp-AMC) |
| カタログ番号GC42706 |
Ac-IEPD-AMCはグランザイムBの蛍光基質です。
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Sample solution is provided at 25 µL, 10mM.
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Ac-IEPD-AMC is a fluorogenic substrate for granzyme B. Upon enzymatic cleavage by granzyme B, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify granzyme B activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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