Fucosylated Ganglioside GM1 (ammonium salt) |
| カタログ番号GC43707 |
フコシル化されたガングリオシドGM1は、もともとウシの甲状腺組織から発見されたフコースを含むグリコスフィンゴ脂質です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Fucosylated ganglioside GM1 is a fucose-containing glycosphingolipid that was originally found in bovine thyroid tissue. It has been found in isolated human small cell lung cancer (SCLC) tumors but is rarely found in other types of lung cancer tumors or normal tissue. Fucosylated ganglioside GM1 is shed from SCLC cells in vitro and in vivo in SCLC nude mouse xenograft models and can be detected in human plasma. It binds to cholera toxin when expressed in rat C6 glioma cultured cells, increasing intracellular cAMP to similar levels as cells expressing ganglioside GM1 .
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