GTP 14564 |
カタログ番号GC43795 |
GTP 14564は、III類受容体チロシンキナーゼの阻害剤であり(c-Fms、c-Kit、ITD-FLT3に対するIC50が0.3μMであり、PDGFRβに対しては1μMです)、。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 34823-86-4
Sample solution is provided at 25 µL, 10mM.
GTP 14564 is an inhibitor of class III receptor tyrosine kinases (IC50s = 0.3 µM for c-Fms, c-Kit, ITD-FLT3 and 1 µM for PDGFRβ). It is without effect against a panel of non-receptor tyrosine and serine/threonine kinases. GTP 14564 blocks the proliferation of leukemia cells stimulated with FLT3 ligand by preventing the activation of STAT5.
Average Rating: 5
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