Histone H3K27Me1 (15-39)-K-biotin (trifluoroacetate salt) (Synonyms: Lys(Me1)27-Histone H3 (15-39)-K(Biotin), Histone H3 (15-39) (Lys27me1), APRKQLATKAAR-K(Me)-SAPATGGVKKPH-K(Biotin)-NH2) |
カタログ番号GC43844 |
Histone H3K27Me1(15-39)は、ヒトヒストンH3.1およびH3.2配列のアミノ酸残基16-40に対応する、ヒストンH3のペプチドフラグメントです。
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Sample solution is provided at 25 µL, 10mM.
Histone H3K27Me1 (15-39) is a peptide fragment of histone H3 that corresponds to amino acid residues 16-40 of the human histone H3.1 and H3.2 sequences. It is monomethylated at lysine 27 and biotinylated via a C-terminal lysine linker. Monomethylation of histone H3 at lysine 27 is associated with actively transcribed genes and positively correlates with H3K36 trimethylation. Levels of H3K27Me1 are increased in patients with metastatic hormone-na?ve and castration-resistant prostate cancer.
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